Fe2+ in heme becomes oxidized to Fe3+ Essay Example for Free

Fe2+ in heme becomes oxidized to Fe3+ EssayConsumers associate bright red color with fresh meat and chromatic tint to outdated, possibly spoiled meat no matter what the pull date says. Some vendors ar treating the cut meat with CO before packaging in plastic wrap for supermarket meat counters. why would this help sales? CO binds to oxygen binding site and this binding is not readily reversible. indeed Hemoglobin remains in saturated form and appears red and fresh. This would definitely enhance sales. CH2OH 5. a. In the icon to the right, what type of truss links the two carbohydrate monomers together? settlement by checking in the spaces(s) provided below. OH invert whole that apply or check none of the above if none of the descriptions apply to the bond shown. _____ glycosidic bond _____ hemiketal bond _____ beta 1-6 linkage _____ester bond ____ ketal bond _____ a furanose bond _____ phosphodiester bond _____ alpha 1-4 linkage _____ a pyranose bond _____ hemiacetal bon d _____ alpha 1-6 linkage _____ none of the above_____ acetal bond _____ beta 1-4 linkage b. Is it doable that the figure shows part of glycogen? YES NO Explain.In your explanation, include at least two types of clues that crumple you the help. For full credit, use precise terminology. No more than two sentences -one per clue be needed to answer this question. Glycogen is a polymer of ? -D-glucopyranose. It contains ? (1? 4) linkages and some ? (1? 6) links. 6. You are studying an enzyme that catalyzes the reaction turning substrate S into fruit P and obeys.Michaelis-Menton kinetics. You are conducting a series of enzyme assays to determine the Vmax of the enzyme each(prenominal) successive assay uses the same core of enzyme, but a different concentration of S. a. When the concentration of S is 10% of the Km, you measure a reaction velocity of 1 ? mole P produced per minute. What is the Vmax for the enzyme? Show all your work and include units at all steps. V= Vmax. S/KM+S V=1 ? mole/min 0. 1Km=S Vmax = V*(Km+S)/S = 1*(Km+0. 1Km)/0. 1Km =1. 1/0. 1Km=0. 11Km The value of Vmax provide be 0.11 times the Michaelis-Menton constant for the given reaction. b. When you add a position concentration of compound C to the reaction mixture of enzyme and substrate at 1/10 the KM, you take note the harvest-home is produced at a much lower rate than when compound C is not present. However, if you ingeminate this experiment with the same concentrations of compound C and enzyme but a very high concentration of substrate, product is produced at about the same rate as the one you calculated in part a. base on the evidence presented, compound C must be (please circle all that apply)a zymogen a competitive inhibitor an allosteric activator a non-competitive inhibitor an endergonic compound a transition state analog 7. Answer each question TRUE or off. If you mark it false, provide a complete explanation of what is slander with it. . a) Enzymes increase the stability of the product of a desired reaction by allowing ionizations, resonance and isomerization not normally available to substrates. ____TRUE ____ FALSE The think this statement is false is ionizations, resonance and isomerization increase the derangement of the substrate.b) Lowering the affinity of hemoglobin for oxygen increases the effectiveness with which it delivers oxygen to the tissues, though it may decrease the totality of oxygen acquired in the lungs. ____TRUE ____ FALSE The mind this statement is false is c) Whether the ? G for a reaction is larger, smaller or the same as ? G0 depends on the concentrations of the compounds that participate in the reaction. ____TRUE ____ FALSE The reason this statement is false is d) Enzymes are potent catalysts because they drive reactions to completion while other catalysts drive reactions to equilibrium. ____TRUE____ FALSE.The reason this statement is false is catalyst lowers the efficacy barrier to a reaction, increases the fraction of molecules that have enough energy to attain the transition state and hence make the reaction go faster in twain directions. e) The hydrolysis of adenosine triphosphate has a large negative ? G0, nevertheless it is stable in solution receivable to the ionization of the phosphates. ____TRUE ____ FALSE The reason this statement is false is f) L-Malate + NAD+ - oxaloacetate + NADH + H+ ? G0 = +29. 7 kJ/mol The reaction as written may occur in some cells at some concentrations of substrate and product.____TRUE ____ FALSE The reason this statement is false is this is a step in the Krebs cycle and occurs in all respiring cells. g) Linking the endergonic reaction X -Y to a second, energetically favorably reaction Y-Z will shift the equilibrium constant of the first reaction. ____TRUE ____ FALSE The reason this statement is false is h) Non-covalent interactions are in any case weak to influence the three-dimensional structure of macromolecules. ____ TRUE ____ FALSE The reason this stat ement is false is tertiary structure is basedon non-covalent interactions. i) Starch and glycogen are both polymers of ?-D-glucose. ____TRUE ____ FALSE The reason this statement is false is they are ? -D-glucopyranose polymers. j) Enzymes bind a transition state intermediate such that it cannot be converted back to substrate. ____TRUE ____ FALSE The reason this statement is false is k) When the reactants and products are all in equal concentrations, no further transpose in concentration will take place. ____TRUE ____ FALSE The reason this statement is false is l).The rate of migration of a protein through an SDS-polyacrylamide gel is not influenced by the charge of the protein. ____TRUE.____ FALSE The reason this statement is false is m) In general, when ATP hydrolysis is coupled to an energy-requiring reaction, the actual reaction often consists of the transfer of a phosphate group from ATP to another substrate, rather than the actual hydrolysis of ATP ____TRUE ____ FALSE The rea son this statement is false is 8. Downugo, a marketed drug widely used by diabetics with hypertension, is metabolized by the liver enzyme CYP3A4. Your company is developing an insulin mimetic. You have three hopeful candidate compounds, all of which are metabolized by CYP3A4.The table below shows the KD of the binding of the molecule to the insulin receptor and the IC50 for each compound as a competitor for Downugo metabolism by CYP3A4. Compound KD for insulin receptor IC50 for CYP3A4 vs Downugo A 10? M 8 mM B 10 nM 50 nM C 5 nM 200 nM Your company has the resources to take only one compound into further development. Based on these results, which is your selection? Explain briefly. A. Very low quantities should be required for binding with insulin receptor, but the IC50 set must also be higher.